
Berlin Hauptbahnhof, where the EuroCity from Prague terminates on the upper level.
Photo: Benjamin Janecke / Wikimedia Commons (CC BY-SA 3.0)Prague to Berlin by Train
An international route between Czechia and Germany.
Reviewed by Eurotraintrip on 2026-07-30
- Duration
- 3h 50m – 4h 15m
- Price from
- 19 EUR
- Distance
- 388 km
- Operators
- EuroCity (DB/CD)RegioJet
- Frequency
- Around six daily EuroCity departures in each direction at roughly two-hour intervals, plus RegioJet's own separate daily schedule
Compare and book Prague–Berlin tickets
Check pricesWhat makes Prague to Berlin different
- EuroCity trains on this corridor are jointly operated by more than just Germany and Czechia - on services that continue past Prague toward Vienna or Budapest, OBB and Hungary's MAV are also involved, reflecting this route's role as one leg of a longer Berlin-Prague-Vienna/Budapest through-corridor rather than a standalone city pair.
- Engineering works mean that every Monday from 16 March to 12 December 2026, this route's EuroCity timetable is cut back to just three trains - the 17:28 and 19:28 departures from Berlin and the 06:31 from Prague - while a fuller roughly-two-hourly service runs on every other day of the week.
- Some EuroCity departures on this route also call at Berlin Sudkreuz and Berlin Ostbahnhof before terminating at Hauptbahnhof, so travelers based in southern or eastern Berlin don't necessarily need to backtrack into the city center to catch this train.
Prague station
Departs from Praha hlavni nadrazi, where automated touch-screen luggage lockers (two sizes, card or CZK cash, roughly 50 CZK for 24 hours) and a staffed left-luggage office operate from 06:00 to 23:00; the Metro Line C entrance sits directly beneath the departure hall, with escalators surfacing right into the main concourse.
Berlin station
Arrives at Berlin Hauptbahnhof's upper level, the same platforms used by this site's Munich and Amsterdam trains into Berlin; self-service luggage lockers are clustered on the lower level near the shopping concourse, a contrast with Praha hlavni nadrazi's staffed left-luggage counter at the Prague end of this same journey.
Train vs. other options
There's essentially no direct scheduled flight between Prague and Berlin given the short distance, so the roughly 4-hour train is the fastest realistic option without a connection; driving the same 388km via the A13 and D8 motorways takes about 4 hours non-stop, similar to the train on paper, but that excludes finding parking near Berlin Hauptbahnhof or central Prague, both areas where the train drops you within walking distance of the sights instead.
Booking tips
- EuroCity advance-purchase fares start from about EUR 19 in second class and rise closer to departure, so book a few weeks ahead on either EuroCity or RegioJet for the cheapest seats.
- From 16 March to 12 December 2026, engineering works mean every Monday sees this route's EuroCity service cut back to just three departures - the 17:28 and 19:28 trains from Berlin and the 06:31 from Prague - so check the day of the week before you lock in a Monday booking.
- RegioJet and EuroCity run on completely separate ticketing systems and loyalty schemes, so it's worth comparing both operators' own websites rather than assuming one aggregator shows every fare.
Good to know: RegioJet and the DB/CD-run EuroCity service are two entirely separate operations on this line - a RegioJet ticket won't be honored on a EuroCity departure or vice versa - and only EuroCity is affected by the reduced Monday timetable running from 16 March to 12 December 2026, so RegioJet can be the more reliable Monday option during that stretch.
While you're in Berlin

The Brandenburg Gate, Berlin's best-known landmark and a former symbol of the city's Cold War division.
Photo: Norbert Nagel / Wikimedia Commons (CC BY-SA 3.0)Berlin trades postcard prettiness for sheer historical density - the Brandenburg Gate, the Reichstag's glass dome, and a preserved mile-plus of the Wall at the East Side Gallery all sit within a short ride of each other, alongside a museum and nightlife scene that easily fills more than a day trip.
Full Berlin travel guide →Frequently asked questions
How long does the train from Prague to Berlin take?
EuroCity trains take roughly 3 hours 50 minutes to 4 hours 15 minutes to cover the 388km, depending on stops; RegioJet runs on a broadly similar schedule.
Which operators run trains from Prague to Berlin?
Jointly-run EuroCity services (Deutsche Bahn and Ceske drahy, with some through-carriages involving OBB) and the private Czech operator RegioJet both run direct daily trains.
Does the 2026 Monday schedule change affect this route?
Yes - from 16 March to 12 December 2026, engineering works cut EuroCity service back to just three trains on Mondays (the 06:31 departure from Prague, and the 17:28/19:28 from Berlin); RegioJet's own schedule isn't affected.